Friday, July 27, 2007

Modafinil - For The Overachiever in You!

(I copied this post from an old blog I used to write in reply to another blogger's post asking about info on this drug)

Humans have a long history of using pharmacology to alter their daily experiences and abilities. Look at caffeine for the most basic and socially accepted example of this. Well, I have jumped on the bandwagon it seems. When I was young I was diagnosed as being ADD and was put on methylphenidate (Ritalin) for a short time to help me in school. I was on it for a while, but after quitting high school and becoming a mechanic I did not see the point. For one reason or another, I stopped taking it and never really thought much about it. There is a point to this story, but some background first...

My thoughts have always raced to some extent, bouncing from this to that. It is actually a real benefit when you are riding motorcycles and in other situations where your attention needs to jump from item to item quickly. Throughout my life this has made certain tasks difficult, but I was always capable of succeeding to some extent. Maybe not doing "A" work, but at least "B" work. Academically I was never super strong, but I was effective in real life. I am a great multi-tasker. I could take on numerous jobs and get multiple things accomplished very quickly by juggling them all at the same time. I have to admit, my work occasionally lacked a certain depth or polish but the result was there. I just did not have the attention span to worry about dotting very single i or crossing every single t.

(you are thinking, of course he is going into emergency medicine....)

Occasionally, I would find one thing that would grab my attention and in a fit of obsessive focus I would accomplish a single task in about 20% of the time of most other people. I loved these moments of productivity, but they were rare and I could not control them. When something grabbed me in a certain way I would focus, otherwise I would drift from thing to thing. This tendency has become very apparent in medical school where I am required to sit in a chair for hours on end staring at words that are as dry and meaningless as a stale bag of Bugles. These texts have no life, no anime to grab my attention and focus me like a patient does. I don't remember what I read.

This has really interfered with my performance for the last two years. In most other endeavors my 60% attention level was enough to get by, but not here. When I considered this possibility and mentioned it to my neurologist we discussed starting Ritalin again. He was against it as I have juvenile myoclonic epilepsy (JME) which is well controlled but we did not want to risk lowering my seizure threshold. I agreed. Recently though, I have been reading a lot about modafinil (Provigil). It seems as if it is a wonder drug because I have not found much in the way of negative effects. I even found one paper where an MD was trying it out to help epilepsy patients deal with the sedative effects of their anticonvulsives! Even better, it is racking up data as a new treatment option for kids with ADHD! It is mainly used for shift workers and narcoleptics, to keep them awake, I thought it would also be perfect for long call nights too now that clerkships are starting. To top it off, it is supposed to have some SSRI effects too! How could it be better??? Maybe it also lowers cholesterol!?

Well, recently I was prescribed some by a local provider to try it out for my ADD like symptoms. This is the perfect time as I am studying for my Step 1 boards and I have no other real responsibilities outside that. I want to see if it would improve my concentration and NOT exacerbate my seizures (which are well controlled on levetiracetam, another great drug!). I did not want to try something like this while I was in a clerkship if it could have bad effects with the JME.

So far I would like to say that it is AMAZING! I focus without difficulty now and remember what I am studying! I stay awake for 16 hours easily but then fall asleep without trouble when I choose. It does not increase myclonic activity in any way that I can see and I have not had any seizures or the threat of any that I can notice. In addition, my mood is much improved too, perhaps due to my new feelings of productivity or its supposed SSRI-like effects too. What is not to like about this drug?!

Anyone else have experience with this drug they want to share?

PS: Here is a great article where the author diaries his modafinil experiment from Slate online magazine!

Monday, July 23, 2007

I Don't Believe In Astrology!

How can I ignore this great prediction/observation of what is going on with my "Leo the Lion" self? This is from this week's Stranger, a local Seattle alt-news rag that comes out weekly.
Leo (July 23 - Aug 22)
How should we visualize this phase you are in? Are you coming back home after a harrowing journey to the abyss? Or are you about to launch a quest straight into the heart of the dawn's blinding promise? Paradoxically enough, Leo, you're doing both! Your coming and going at the same time. Your graduating from an ancient lesson and beginning a new course of study. Hints of the future are mingled with the last gasps of the past.
Wow, how can I ignore that? I am about to take my Step 1 medical boards, which will get me out of the classroom forever. In case you have not been reading, these last two years have been HELL for me! I am so excited about the hospitals and clerkships and have this one last hurdle to jump. Sounds pretty accurate, eh?

Saturday, July 21, 2007

The Meaning of Life

This is definitely a good little video and something to return to occasionally. I found this on Graham's blog, "OverMyMedBody!"

Tuesday, July 17, 2007

I See Elves.... Everywhere

The brain is a strange place.... and they said said that there is no such thing as Santa Claus! Shadowfax over at Movin' Meat really hit the jackpot on this one.

This has to be the best all-time patient presentation I have ever heard of.

Hell, the paramedics I used to run with never had one to top this and they have ALL the good stories!

I Miss Seattle...

Seattle used to be a place where things happened, people took risks in both education, policy, music and politics. We were progressive and focused on our communities. What happened?

http://seattletimes.nwsource.com/html/localnews/2003792948_webcyclists17m.html

What happened to Seattle? My car was stolen two months ago and it was broken into AGAIN last week. Not to mention the other 2 stolen cars on my SAME block in 6 months and the thefts, drug deals, etc... that are occurring in my Ballard neighborhood. Glad the police have prioritized naked bikers. Police are really not to blame though, when the public complains they have to respond. Where did these people come from? Redmond? Sure, nude people on bicycles are shocking, but waste the police on such a peaceful protest?

Seattle used to be all about alternative, environmental, experimental & practical types of people. Now it is full of overpaid whiners that vote on everything 6 times before they finally give up on it and drive home in their single occupant vehicles! (Hey, why you complaining, it runs on biodiesel!) Yeah? Defeats the purpose when you put it in your $40k Hummer, with only you in it and then drive back to your $700k condo don't you think?

Somewhere in 1999:
"Gee, should we build mass transit? Sounds like a good idea... wait, someone will be unhappy if we put it too close to their house. Maybe we can put it somewhere that won't inconvenience anyone. Yeah, that sounds good. How about eastern Washington? Then we can build a big parking lot and we can all drive there to get on and be shuttled to downtown. Wait, the farmers might not like that. Hmmm... we should vote again. What? It is 2007 already?"

Monday, July 9, 2007

A View From Inside Iraq

My mother and I do not necessarily see eye to eye when it comes to politics and our opinions differ on many current social topics. We each have our views and mine tend to be a lot more liberal than hers, even though I consider myself somewhat of a moderate. Our political relationship is not antagonistic in any way, we simply know where the other stands and choose to avoid arguing certain points. The true benefit of this sort of relationship is that we each expose one another to many views and opinions we would not find in our regular circles.

Recently, this was the case with a source of online reporting about the war in Iraq. Although many of the items my mother sends in my direction seem to have a message meant for more conservative ears than mine, I do try and look at each and evaluate it for myself. Recently, she told me that some of the best writing on the war in Iraq, the people of Iraq and the soldiers there was being done by a guy named Michael Yon (more about who he is here) Over the past weeks I have added his blog (now an online magazine) to my reading list and skimmed each "dispatch" as it comes in. I know Michael Yon has a slightly different political bent than myself but his writing (an photography) is not only good, but compelling and honest in a refreshing manner. I still hope to read more before I come to a final judgment but his photos, opinions and take on the events in Iraq seem truly insightful and for lack of a better term, real. This is mainly because he is there with the soldiers. As an ex-special forces officer himself, he knows how to get in with the soldiers and get to where the news is happening. He does not call himself a journalist, simply a writer and photographer, and his writing tells a story.

Please take the time and check out his online magazine for yourself. There is also a small writeup about how he funds his writing, which is one of the first things I read. I would love your feedback on what you know of Michael Yon and his writing as well.

Tuesday, July 3, 2007

The 2007 "Mountains to Sound" 100 Mile Race Champions!

My friends Mark Rieder & Josh Smith (team #256, "Hurt Me Like You Mean It") are the new, 2007 Masters Pairs champions of the Mountains to Sound 100 mile race!

Nice work guys. To top it off, it was Mark's 37th38th Birthday! Happy Birthday, now everyone knows! I tried to help them shuttle some stuff and rode my bike along the route and photographed them. The photo above is linked to a photo album of the event and is a compilation of everyone's photos that day. If you click here, you can check out the results and how they were about a half hour ahead of the second place team!!!

My goal is to get my back in shape again and pariticpate in a race like this with these pros one day soon... or not soon.... must be realistic.

Sunday, July 1, 2007

Its Not The Books That Are Hard Here...

Well, I have some good news. Evidently, a 15 question internet survey has confirmed my original decision to become a doctor despite my recent doubts! (see below) I have to admit, over these last few weeks since school ended I have myself wondered long and hard if I am making the right decision. The first two years of medical school have been very hard for me. Not the book work, which is both mind stimulating and mind numbing at the same time. That is tedious and hard for someone so ADD as myself to focus on when all I see are words on a page. I need life, experience & challenge to focus my thoughts and solidify my memory. No, that has not been the hardest part.

There is a certain amount of urban wisdom about how different people handle medical school. It seems there are three dominant types of medical students (although other's have claimed there are 12 types!). There are those that easily excel in the first two years of books and lectures but have a lot of difficulty (emotional or intellectual) adapting to the world of patients, life & death. There are the opposite, those that struggle in the lecture hall but seem to come into their stride in the clerkships where they feel more effective, practical and motivated to learn about the person/patient in front of them. Finally, there are the gunners, the chosen few, the gifted. The future chief cardiothoracic surgeons of the world or simply the excellent family doctor that becomes legend in the area in which they practice. They excel and enjoy the first years of books and when the clerkships begin they also seem to slide naturally into the clinical rhythm, reveling in the new experiences and opportunity to apply all that they learned the first two years. As expected, the last type is the rarer breed and envied/despised by many of the other two. The hardest thing for me in medical school is realizing that I am not that last type as much as I had expected to be. I am seriously hoping that I am the second type at the very least, because I need to excel soon or these negative feelings will win.

I fatigued of the lecture hall early on and have a hard time focusing on books, words and PowerPoint presentations. When I became an EMT I was in love with the didactic portion of training, but it was short, to the point and we were soon in the field dealing with people in trouble in their crushed cars, living rooms or kitchen floors as their hearts stuttered or they struggled for air. With every real world experience with someone in trouble it doubled my craving for more knowledge in hopes that I could help or at least not hurt these people. You would sit in class for a few days studying the musculoskeletal basics and the next day you would be trying to assess, treat and comfort a mother and her 3 children after their car rolled on a late night drive home in the mountains. I was an "intermediate" EMT which meant I could give some drugs and had more medical decision making responsibility than most EMT's, but not as much as paramedics. It was a world that favored street smarts, thinking on your feet, finding quick solutions to get the job done. People's lives depending on my decisions. I seemed to excel as an EMT and at one point was the director of our small, rural EMS department. I enjoyed everything from patient care, to ordering supplies for the ambulance to spending the day in the fire station polishing the lights and chrome when there were no calls. With a background in academia and research this was a great contrast and it felt intoxicating to love something and be so good at it and truly offer something of value to those around me in an immediate and tangible manner. It took another EMT to point out the fact that if I loved this so much, I should leave my research career and become an MD....and here I am. Now I sit in lecture halls or in coffee shops reading and regurgitating Latin words and obscure facts about very rare conditions that I will likely never see in practice.

I thought medical school would be a more intense and rewarding version of being an EMT. Perhaps at some point it will be. What I also did not bargain for is the amount of competition there is in medical school. Not so much among one another, but us against the system. As in many things in my life, I came to this with high hopes and expectations and that is always my first big mistake. Medical school takes the top students from all across the country and then makes them compete against one another for the few student slots. I think the average is 1 student accepted for every 7 applying. This ratio varies greatly by school and at a place like UW School of Medicine, the #1 primary care medical school in the country for over 10 years, it becomes insane. I was dedicated though and armed with my experience as an EMT. I knew that I was good at this and I knew that I would excel. It felt like I finally discovered who I truly was, what my talents were and I was motivated to follow it. It took my two attempts at applying and 2-3 years of prep work beforehand (I was a physics major in college and needed many medical pre-requisite classes). I finally made it at the age of thirty-five.

The hardest part of all this for me is that I am suddenly in a world very different from anything I have ever known. I am now competing with the best, brightest and most capable people our colleges and universities produce. It is not so easy to rise to the top as before. In addition, I am much older than most of my cohort and this separates me from them in subtle yet meaningful ways. It is not so much the books that are hard, although they are not easy by any means, they are simply fatiguing. What is hard is when you struggle for mediocre grades when you thought this was your calling and that you would excel. It is hard watching your life of before, friends and activities, atrophy with the hours of coursework. It is hard seeing every crack in your emotional foundation start to widen under the stress. It is hard seeing your faults and your shortcomings every day, not only in school but how you deal with your personal relationships under such stress. It is hard to be in your thirties and see your friends getting married, having children, buying and remodeling houses and living a life while you are buried in books at some coffee shop every day. It is hard realizing that you are exerting 110% of the ability and energy you have to simply stay afloat in a world that does not utilize your talents and seeing yourself in the lower half of the class day after day, especially when you felt you would be good at this. It is hard when the few friends you have in your life move on in their lives and you become a memory to them. It is hard to see that your health (emotional and physical) and deteriorated under the workload and endless hours in uncomfortable lecture hall seats. It is hard when you find yourself making the decision to abandon someone that loves you very much and that you know is one of the best people you have ever been in a relationship with simply because you can't stand failing at one more thing, because you are in survival mode and the only way you know how to function is alone and focused on your task at hand. It is hard to see yourself hurt them and all the while you are only getting older. It is hard to see yourself fail them when it feels you are failing most everything else in your life, when you are struggling to stay on top. It is hard realizing that most things in your life are now memories or dreams of what the future might hold and you are getting nothing back from medicine even though you have dedicated everything to it.

Now classes are over and I am supposed to be studying for my medical boards. The sun is out and my time is my own. I have my clerkship schedule and I am about to head into the hospitals where I hope that medicine will redeem me in some way. But before that I need to study for my medical board exams, the first step of three, but I am struggling. I seem beat down and tired and I don't care about these words on paper anymore. Now that I have been thrown back into my life with full days and evenings to myself I see how empty it has become without exams, lectures and deadlines consuming my hours and minutes. I am dog sitting for friends that are in the Grand Tetons and staying at their house while they are away. The house is filled with photos of families and friends and ski trips and backpacking trips. Their are photos of barbecues and house remodeling parties and my face is in none of them because I have not existed for the last 3 or so years and it hurts. And in all this I wonder what I am doing to myself and my life and whether or not this stuff is worth it. I have written about this to others and some that have gone through this process for their MD or other professional degree have returned my correspondence with a single refrain. "It will get better, hang in there." I must say that these short sentences of hope are really helpful, because I can't see it right now.

I know this is a depressing post, but it is where my head is at. I am about to turn 37 years old and I am single, about to be homeless for the next year and am selling all my possessions for the transient life my clerkship schedule demands. I will travel to a new city every 6 weeks for a new medical specialty rotation. Some will be here in Washington and some in Alaska, so I need to travel light. Still, I look around at my friends and wonder if I will ever have a life outside this anymore. What is hard is seeing those few others in your class that are doing well in school, doing well in their marriages, having children, buying houses and excited about clerkships. How do they do it? I think they were simply happier, better balanced and capable people before this all started and what is hard is seeing that you are not. Not that you are worthless or a complete failure, but not what you hoped you would be, not what you imagined you would be. Now perhaps it makes sense why I felt a small glimmer of hope when this stupid internet questionnaire, designed as a goofy distraction, telling me I should be pursing an MD after answer a few silly questions. I needed the reminder, because I don't really know anymore it seems.

You Should Get a MD (Doctor of Medicine)

You're both compassionate and brilliant - a rare combination.
You were born to be a doctor.